Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MED13 All Species: 19.09
Human Site: S1602 Identified Species: 35
UniProt: Q9UHV7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UHV7 NP_005112.2 2174 239318 S1602 A G I S G E S S S L P T Q P H
Chimpanzee Pan troglodytes XP_001138050 2188 240763 S1616 A G I S G E S S S L P T Q P H
Rhesus Macaque Macaca mulatta XP_001110128 2174 239364 S1602 A G I S G E S S S L P T Q P H
Dog Lupus familis XP_537704 2182 240593 S1610 A G I S G E S S S L P A Q P H
Cat Felis silvestris
Mouse Mus musculus Q5SWW4 2171 238573 L1601 I S G E S A S L P T Q P H P D
Rat Rattus norvegicus NP_001100505 2040 223488 D1495 V G I P T D G D S H A I T Y P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509907 2170 238695 S1598 T T G I S G E S S A V P A Q P
Chicken Gallus gallus XP_415884 2225 244861 T1653 A G M S G D A T T A P A Q P H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio A2VCZ5 2102 230974 S1545 G T L G D A T S A T S Q P Q V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KTX8 2618 280005 K2044 P M E T N E I K Q E P G V G K
Honey Bee Apis mellifera XP_393643 1982 216109 P1437 E P F S L G G P E D P D R R R
Nematode Worm Caenorhab. elegans Q93442 2862 325119 A2299 A I L A F I R A F N S I M C K
Sea Urchin Strong. purpuratus XP_001203054 1127 123639 D582 L E T V T P R D S E Q P P A V
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.8 97.7 94.1 N.A. 92.5 87.8 N.A. 89.5 84.6 N.A. 64.8 N.A. 24.7 35 21 25.7
Protein Similarity: 100 98.3 98.4 96 N.A. 96.4 91.2 N.A. 94 90.5 N.A. 76.9 N.A. 41.3 51.5 37.4 36
P-Site Identity: 100 100 100 93.3 N.A. 13.3 20 N.A. 13.3 53.3 N.A. 6.6 N.A. 13.3 13.3 6.6 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 13.3 26.6 N.A. 13.3 86.6 N.A. 26.6 N.A. 20 20 26.6 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 47 0 0 8 0 16 8 8 8 16 8 16 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % C
% Asp: 0 0 0 0 8 16 0 16 0 8 0 8 0 0 8 % D
% Glu: 8 8 8 8 0 39 8 0 8 16 0 0 0 0 0 % E
% Phe: 0 0 8 0 8 0 0 0 8 0 0 0 0 0 0 % F
% Gly: 8 47 16 8 39 16 16 0 0 0 0 8 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 0 0 8 0 39 % H
% Ile: 8 8 39 8 0 8 8 0 0 0 0 16 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 16 % K
% Leu: 8 0 16 0 8 0 0 8 0 31 0 0 0 0 0 % L
% Met: 0 8 8 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 8 0 0 0 0 8 0 0 0 0 0 % N
% Pro: 8 8 0 8 0 8 0 8 8 0 54 24 16 47 16 % P
% Gln: 0 0 0 0 0 0 0 0 8 0 16 8 39 16 0 % Q
% Arg: 0 0 0 0 0 0 16 0 0 0 0 0 8 8 8 % R
% Ser: 0 8 0 47 16 0 39 47 54 0 16 0 0 0 0 % S
% Thr: 8 16 8 8 16 0 8 8 8 16 0 24 8 0 0 % T
% Val: 8 0 0 8 0 0 0 0 0 0 8 0 8 0 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _